IBD Medication Guide



Brand Name(s)

Cipro®, Proquin®

Drug Class


How taken

Oral and intravenous (IV)

Used for

Active Crohn’s disease and pouchitis

Recommendations for Pregnancy

Avoid: potential toxicity to cartilage

Recommendations for Lactation

Limited human data: probably compatible

Medication indication

Cipro is indicated in adult patients for treatment of infections caused by certain bacteria. In IBD, this medication is often used for reducing intestinal bacteria, and Crohn's disease patients who often have fistulas or recurrent abscesses near their anus. This medication may also be used to treat pouchitis.

Indicated for pediatric use

Talk to your doctor about use in children.

Most common side effects

Nausea, vomiting, stomach pain, indigestion, diarrhea, headache, nervousness, agitation, anxiety, difficulty falling asleep or staying asleep


Contains fluoroquinolone, an ingredient associated with an increased risk of tendonitis and tendon rupture. It may also cause worsening of myasthenia gravis (a disease that causes muscle weakness).

Learn more about antibiotics

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