IBD Medication Guide

In
Infliximab
In

Infliximab

Brand Name(s)

Remicade®

Drug Class

Biologics

How taken

Intravenous (IV) infusion

Used for

Moderate-to-severe Crohn’s disease and ulcerative colitis in adults and pediatric patients age 6 and older

Recommendations for Pregnancy

Low risk

Recommendations for Lactation

Limited human data: probably compatible

Medication indication

Indicated for reducing signs and symptoms, and inducing and maintaining clinical remission, in adult and pediatric patients over the age of 6 with moderately to severely active Crohn’s disease who have had an inadequate response to conventional therapy. Infliximab is indicated for reducing signs and symptoms, achieving clinical remission and mucosal healing, and eliminating corticosteroid use, in adult and pediatric patients over the age of 6 with moderately to severely active ulcerative colitis who have had an inadequate response to conventional therapy. Infliximab is indicated for reducing the number of draining enterocutaneous and rectovaginal fistulae and maintaining the fistulizing closure in patients with Crohn’s disease. Infliximab is indicated for reducing signs and symptoms, achieving clinical remission and mucosal healing, and eliminating corticosteroid use, in adult and pediatric patients over the age of 6 with moderately to severely active ulcerative colitis who have had an inadequate response to conventional therapy.

Indicated for pediatric use

Yes, indicated for pediatric use

Most common side effects

Infusion reactions such as hives, redness, chest pressure, itching and swelling of the lips and throat and shortness of breath, respiratory infections, such as sinus infections and sore throat; headache; coughing; stomach pain; nausea; and back pain.

Other

There have been reports of serious infections associated with infliximab, including tuberculosis (TB) and other infections such as viruses, fungi, and other bacteria that have spread throughout the body. On rare occasions certain types of cancer, including lymphoma, have been reported.

To see the full prescribing information for this medication, click here.

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