Oral and injection under the skin (subcutaneous)
Active Crohn’s disease
Recommendations for Pregnancy
Recommendations for Lactation
Contraindicated. Females and males of reproductive potential: Methotrexate may decrease the effectiveness of oral contraceptives. Talk to your doctor.
NOTE: This medication has been typically used for the treatment of Crohn's disease. Talk to your doctor about potential risks and side effects.
Indicated for pediatric use
NOTE: This medication may be recommended for pediatric use. Be sure to talk to your doctor about potential risks and side effects.
Most common side effects
Common side effects include influenza-like symptoms (nausea, vomiting, diarrhea, and low white blood count) hair loss, headache, dizziness, drowsiness, and mouth sores.
Not recommended for individuals with pre-existing liver disease. Known to cause birth defects. It is recommended for patients to stop methotrexate at least three months prior to planned conception. Reduces the absorption of folic acid. Fibrosis and lung inflammation are also rare side effects.
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