IBD Medication Guide



Brand Name(s)


Drug Class

Targeted Synthetic Small Molecules

How taken

oral (by mouth)

Used for

moderate to severe ulcerative colitis

Recommendations for Pregnancy

Recommendations for Lactation

Medication indication

Targeted synthetic small molecules are medications that help reduce inflammation by specifically targeting parts of the immune system. The targets of these medications can play a role in intestinal inflammation. These medications are taken by mouth and there are currently two types of targeted small molecules, both approved for moderate to severely active ulcerative colitis in adults.

Indicated for pediatric use


Most common side effects

Common side effects may include: upper respiratory tract infections, elevated liver enzymes, low blood pressure when you stand up (orthostatic hypotension), painful and frequent urination (signs of urinary tract infection), back pain, high blood pressure, headache


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