IBD Medication Guide



Brand Name(s)


Drug Class

Aminosalicylates (5-ASA)

How taken


Used for

Ulcerative colitis

Recommendations for Pregnancy

Considered low risk; give folate 2 mg daily

Recommendations for Lactation

Limited human data: potential diarrhea. Females and males of reproductive potential: Sulfasalazine decreases sperm count and therefore may cause infertility.

Medication indication

For the treatment of mild-tomoderate ulcerative colitis, and as adjunctive therapy in severe ulcerative colitis, and for the prolongation of the remission period between acute attacks of ulcerative colitis. NOTE: This medication has also been typically used for the treatment of Crohn's disease. Talk to your doctor about potential risks and side effects.

Indicated for pediatric use

NOTE: This medication may be recommended for pediatric use. Be sure to talk to your doctor about potential risks and side effects.

Most common side effects

Diarrhea, headache, loss of appetite, upset stomach, vomiting, and stomach pain


Low sperm count and infertility have been observed in men treated with sulfasalazine; however, withdrawal of the drug appears to reverse these effects

Learn more about aminosalicylates (5-asa)

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