Brand Name(s)
Azulfidine®
Drug Class
Aminosalicylates (5-ASA)
How taken
Oral
Used for
Ulcerative colitis
Recommendations for Pregnancy
Considered low risk; give folate 2 mg daily
Recommendations for Lactation
Limited human data: potential diarrhea. Females and males of reproductive potential: Sulfasalazine decreases sperm count and therefore may cause infertility.
Medication indication
For the treatment of mild-tomoderate ulcerative colitis, and as adjunctive therapy in severe ulcerative colitis, and for the prolongation of the remission period between acute attacks of ulcerative colitis. NOTE: This medication has also been typically used for the treatment of Crohn's disease. Talk to your doctor about potential risks and side effects.
Indicated for pediatric use
NOTE: This medication may be recommended for pediatric use. Be sure to talk to your doctor about potential risks and side effects.
Most common side effects
Diarrhea, headache, loss of appetite, upset stomach, vomiting, and stomach pain
Other
Low sperm count and infertility have been observed in men treated with sulfasalazine; however, withdrawal of the drug appears to reverse these effects
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