IBD Medication Guide

Brand Name(s)

Prograf®

Drug Class

Immunomodulators

How taken

Oral and intravenous (IV)

Used for

Moderate-to-severe Crohn’s disease and ulcerative colitis

Recommendations for Pregnancy

Use if mother’s health mandates

Recommendations for Lactation

Limited human data: potential toxicity

Medication indication

NOTE: This medication has been typically used for the treatment of Crohn's disease and ulcerative colitis. Talk to your doctor about potential risks and side effects.

Indicated for pediatric use

NOTE: This medication may be recommended for pediatric use. Be sure to talk to your doctor about potential risks and side effects.

Most common side effects

Headache, hypertension, diarrhea, constipation, nausea, vomiting, heartburn, stomach pain, loss of appetite, difficulty falling asleep or staying asleep, dizziness, weakness, back or joint pain, burning, numbness, pain or tingling in the hands or feet, rash, and itching

Other

Avoid eating grapefruit or drinking grapefruit juice while taking tacrolimus. There is a small risk of infections, skin cancer, kidney dysfunction; close monitoring is needed.