Oral and intravenous (IV)
Moderate-to-severe Crohn’s disease and ulcerative colitis
Recommendations for Pregnancy
Use if mother’s health mandates
Recommendations for Lactation
Limited human data: potential toxicity
NOTE: This medication has been typically used for the treatment of Crohn's disease and ulcerative colitis. Talk to your doctor about potential risks and side effects.
Indicated for pediatric use
NOTE: This medication may be recommended for pediatric use. Be sure to talk to your doctor about potential risks and side effects.
Most common side effects
Headache, hypertension, diarrhea, constipation, nausea, vomiting, heartburn, stomach pain, loss of appetite, difficulty falling asleep or staying asleep, dizziness, weakness, back or joint pain, burning, numbness, pain or tingling in the hands or feet, rash, and itching
Avoid eating grapefruit or drinking grapefruit juice while taking tacrolimus. There is a small risk of infections, skin cancer, kidney dysfunction; close monitoring is needed.
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