IBD Medication Guide



Brand Name(s)


Drug Class

Janus Kinase Inhibitors

How taken


Used for

moderate to severe ulcerative colitis

Recommendations for Pregnancy

Risks associated to mother and fetus in pregnancy. Pregnancy planning should be considered in women of reproductive age.

Recommendations for Lactation

No information on presence of this medication within human breast milk. Tofacitinib was found present in milk of lactating animal models. Breastfeeding while taking this medication is not advised.

Medication indication

moderate to severe ulcerative colitis

Indicated for pediatric use

Not currently approved for pediatric use. Safety and effectiveness of this medication in children is not established.

Most common side effects

Common side effects may include infections in nose or sinus, headache, nausea, diarrhea, rash, throat irritation, high cholesterol, gastroenteritis, anemia, upper respiratory infection. Risks of lymphoma and other cancers are rare.


Patients should be tested for tuberculosis prior to starting tofacitinib. Avoid taking live vaccines while taking tofacitinib. .

To see the full prescribing information for this medication, click here.

Learn more about janus kinase inhibitors

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